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Nanosensors could help determine tumors’ ability to remodel tissue

MIT researchers have designed nanosensors that can profile tumors and may yield insight into how they will respond to certain therapies.

Illustration: Christine Daniloff/MIT

Measuring enzyme levels could help doctors select appropriate treatments. MIT researchers have designed nanosensors that can profile tumors and may yield insight into how they will respond to certain therapies. The system is based on levels of enzymes called proteases, which cancer cells use to remodel their surroundings. Once adapted…

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To produce biopharmaceuticals on demand, just add water

Researchers at MIT and other institutions have created tiny freeze-dried pellets that include all of the molecular machinery needed to translate DNA into proteins, which could form the basis for on-demand production of drugs and vaccines.

Image: Christine Daniloff/MIT. Antimicrobial peptide illustration by Ymahn/Wikimedia Commons.

Freeze-dried cellular components can be rehydrated to churn out useful proteins. Researchers at MIT and other institutions have created tiny freeze-dried pellets that include all of the molecular machinery needed to translate DNA into proteins, which could form the basis for on-demand production of drugs and vaccines. The pellets, which…

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Faculty Spotlight: Leonid Mirny

Leonid Mirny

Exploring the Genome in 3D Since 2008, Leonid Mirny, Professor of Medical Engineering and Science, and Physics, has worked to understand the human genome in 3D with his team at MIT in collaboration with the Dekker Lab at UMass Medical School. Using new data uncovered via Chromosome Conformation Capture (Hi-C)…

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