George B. Benedek

Associate Faculty
Phone: (617) 253-4828
Website: Benedek Group
Lab Phone: (617) 253-4828
room: 13-2005
MIT address: 77 Massachusetts Ave., Cambridge, MA 02139
Administrative Assistant: Monica Wolf
assistant phone: (617) 253-4829
assistant email: mwolf@mit.edu

George B. Benedek

Associate Faculty

title(s)

  • Alfred H. Caspary Professor of Physics and Biological Physics and of Health Sciences and Technology, Massachusetts Institute of Technology

degrees

  • PhD in Physics, Harvard University, 1953
  • AM in Physics, Harvard University, 1952

selected awards/societies

  • Proctor Medal Award by the Association for Research Vision and Ophthalmology (ARVO)
  • Recipient of the American Physical Society Irving Langmuir Prize in Chemical Physics

 

research

The research of the Benedek group centers on phase transitions, self-assembly and aggregation of biological molecules. These phenomena are of biological and medical interest because phase separation, self-assembly and aggregation of biological molecules are known to play a central role in several human diseases such as cataract, Alzheimer’s disease, and cholesterol gallstone formation. A combination of experimental work, theoretical analysis, and computer simulations is used to understand the connection between the basic interactions amongst the molecules and the resulting condensed phases.

selected publications

  • O. Annunziata, N. Asherie, A. Lomakin, J. Pande, O. Ogun, and G. B. Benedek. “Effect of polyethylene glycol on the liquid–liquid phase transition in aqueous protein solutions.” Proc. Natl. Acad. Sci. USA 99 (2002): 14165-170.
  • O. Annunziata, O. Ogun, and G. B. Benedek. “Observation of liquid–liquid phase separation for eyelens _S-crystallin.” Proc. Natl. Acad. Sci. USA 100 (2003): 970-74.

A full list of Professor Benedek’s publications can be found on his website.

courses taught