Into the Fold: Using Origami to Beat Metastasized Cancer

Contributors: Aikaterini Mantzanivou, Lina A. Colucci, Michael J. Cima
Many advanced cancer patients have tumors growing throughout their abdomen. They need treatment that combines surgery and chemotherapy to kill as many cancer cells as possible while minimizing damage to their body. The Cima Lab has created a thin biomaterial sheet that releases chemotherapy at a low dose over weeks. The ancient Japanese art of origami—in this case, the famous Miura V-pleat, also used in maps and satellites—is applied to fold the sheet and place it inside the patient’s abdomen through a tiny incision. Once inside, it expands to expose as big an area as possible to the drug.

This image and other winners will be on public display in the Koch Institute Public Galleries starting on March 9th, 2018. For more information on the Koch Institute and its Image Awards, click here.