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Alex K. Shalek named 2018 Pew-Stewart Scholars for Cancer Research

Alex K. Shalek, Pfizer-Laubach Career Development Assistant Professor, has been named one of five 2018 Pew-Stewart Scholars for Cancer Research. This program is a partnership between The Pew Charitable Trusts and The Alexander and Margaret Stewart Trust to support promising early career scientists whose research will accelerate discovery and advance…

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Charting the path to better cell models of the intestine

*Photo:┬áImage of a single Paneth cell with anti-microbial granules in red and green, derived from and adult intestinal stem cell, following the small molecule bioengineering approach identified by Mead et al. For many years, drug development has relied on simplified and scalable cell culture models to find and test new…

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MIT engineers recruit microbes to help fight cholera

MIT engineers have developed a probiotic mix of natural and engineered bacteria to diagnose and treat cholera, an intestinal infection that causes severe dehydration. Cholera outbreaks are usually caused by contaminated drinking water, and infections can turn fatal if not treated. The most common treatment is rehydration, which must be…

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A new way to mend a broken heart

After a patient has a heart attack, a cascade of events leading to heart failure begins. Damage to the area in the heart where a blood vessel was blocked leads to scar tissue. In response to scarring, the heart will remodel to compensate. This process often ends in ventricular or…

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