Thomas Heldt

Core Faculty
Phone: (617) 324-5005
Lab Phone: (617) 324-5005
room: E25-324
MIT address: 77 Massachusetts Ave., Cambridge, MA 02139
Administrative Assistant: Chaolyn Clay
assistant phone: (617)253-0009
assistant email:

Thomas Heldt

Core Faculty


  • Associate Professor of Electrical and Biomedical Engineering, Department of Electrical Engineering & Computer Science
  • Core faculty member, Institute for Medical Engineering & Science
  • Principal Investigator, Research Laboratory of Electronics


Thomas Heldt joined the MIT faculty in 2013 as a core member of the Institute for Medical Engineering and Science (IMES) and the Department of Electrical Engineering and Computer Science. Additionally, Thomas is a Principal Investigator with MIT’s Research Laboratory of Electronics (RLE). He directs the Integrative Neuromonitoring and Critical Care Informatics Group in IMES and RLE.

Thomas’ interests began meandering between basic science and clinical medicine in his native Germany, where he started studying physics and medicine at Johannes Gutenberg-Universität, Mainz, Germany. He subsequently received the MS and MPhil degrees in Physics from Yale University and the PhD degree in Medical Physics from the Harvard-MIT Division of Health Sciences and Technology in 2004. He completed postdoctoral training with the Laboratory for Electromagnetic and Electronic Systems at MIT before he co-founded and co-directed the Computational Physiology and Clinical Inference Group at RLE.

In addition to his MIT appointments, Thomas holds courtesy research appointments at Harvard Medical School, Boston Children’s Hospital (Neurology), Massachusetts General Hospital (Emergency Medicine), and Boston Medical Center (Neurosurgery).


  • PhD in Medical Physics, Health Sciences and Technology, MIT, 2004
  • MS and MPhil in Physics, Yale University, 1996 and 1998


Thomas’s research interests focus on signal processing, mathematical modeling, and model identification to support real-time clinical decision making, monitoring of disease progression, and titration of therapy, primarily in neurocritical and neonatal critical care. In particular, Thomas is interested in developing a mechanistic understanding of physiologic systems, and in formulating appropriately chosen computational physiologic models for improved patient care. His research is conducted in close collaboration with colleagues at MIT and clinicians from Boston-area hospitals.

selected publications

Full list of Prof. Heldt’s publications can be found at  .