Postdoctoral Associate – IMES/Isolation and Characterization of Exosomes Project
Postdoctoral Associate to join the team of Dr. Mercedes Balcells-Camps and Professor Elazer Edelman in a research group focused on extracellular vesicles, especially exosomes and microvesicles, which are not merely lipid vesicles, but also carry nucleic acids, proteins, receptors, lipids, and transcription factors, among others. The cargo content of microvesicles is programmed and selected specifically by the secretory cell. Due to its cargo, microvesicles have been implicated in multiple pathologies. Will isolate and separate extracellular and intracellular microvesicles produced by vascular, cancer, and brain cells; characterize isolated microvesicles as function of their size, origin, and load characteristics; and examine if the isolated microvesicles are able to induce phenotypic and genotypic changes on neighboring healthy and diseased cells. Duties include performing original research, which may include mammalian cell culture under 2D and 3D culture environments and mechanical stimulation (flow), differential ultracentrifugation, sequential centrifugal ultrafiltration or immunocapture, cryo-TEM, qRT-PCR, NGS-DNA Seq, SDS-PAGE, flow cytometry, Western blot, immunofluorescence, and cell function assays in high throughput format.
PhD in biology, chemistry, materials science, engineering, or relevant field; post-graduate experience in the biological field; experience with isolation and characterization of cell culture supernatants or serum proteins or lipids from bodily fluids; expertise in biology techniques (RNA, DNA, protein isolation and characterization, metabolomics, proteomics); experience with drug delivery (microparticle synthesis, loading, imaging and sorting techniques), a variety of computational biology techniques, software packages (R, MATLAB, Python), -omics databases, and algorithms to analyze -omics data; ability to work independently and collaboratively; and strong publication record. Experience with animal models and working with hydrogels and perfusion systems a plus.
Please apply to position 15201 through the MIT jobs portal at http://jobs.mit.edu. Posted September 14, 2017
Assistant Director for Administration – IMES
Job Description & Minimum Qualifications
Responsible for the day-to-day personnel, financial, and general operational management of IMES and the HST Program, providing counsel and comprehensive support to the Director of IMES, faculty, students, and other staff members regarding finances, personnel, operations, and other policy matters. Provide interface and promote effective relationships with MIT and Harvard administrations, serve as the senior administrative staff member for HST at HMS, including coordinating and integrating all financial, personnel, and operational matters. Promote effective relationships with area hospitals and affiliated organizations and sponsors. Oversee all administrative elements, including computing, public relations, space planning and renovation, student financial support, strategic plans and budget submission and reconciliation processes. Implement and coordinate new multi-institutional educational and research programs. Identify and seek solutions for problems on all administrative matters, and provide leadership and direction to staff and faculty in adapting to administrative procedures and technology. Supervise financial, personnel, EHS and headquarters staff, including mentoring and career development planning.
- Identify operational problems and deficiencies and recommend solutions to the Director
- Advise and assist all IMES and HST staff, faculty, and students, as applicable, in matters relating to accounting, purchasing, personnel, and general administration
- Coordinate and integrate all personnel, financial and operational functions of IMES and the HST program
- Oversee all aspects of both pre and post award administration of all research, discretionary, and Institute/University funding of IMES and HST at MIT and HST at HMS
- Ensure compliance with sponsor requirements and MIT and Harvard fiscal policies
- Manage annual institutional budget processes and inter-institutional reconciliation processes
- Oversee academic and student fundingOversee all aspects of the payroll process, including the salary certification process and salary distributions
- Oversee all personnel matters and issues including administrative and research staff searches; academic appointments; support staff hiring; visa issues; compensation issues; and promotions. Ensure compliance with affirmative action regulations
- Support IMES Director in faculty hiring, promotion and tenure processes
Manage the annual salary review processes for all IMES and HST employees. Oversee and advise on the annual performance evaluation process
- Oversee the Outside Professional Activities and Conflict of Interest reporting processes
- Recommend salary adjustments, promotions, performance issues and terminations in collaboration with Human Resources Offices at MIT and HMS and with the Directors and SoE Dean’s Office
- Mentor staff and promote career development opportunities
- Maintain clear and regular internal communications via team and individual meetings, emails, and memos
- Oversee facilities issues including short- and long-range facilities renovation and development plans and coordinate with architects, contractors and other facilities personnel
- Oversee space utilization
- Oversee IMES’ compliance with environmental, health and safety regulations and with MIT’s EHS training program
- Manage short- and long-range plans for IT and communications, including IMES and HST web sites
- Oversee and/or assist with developing, producing, and disseminating content related to IMES initiatives—people, programs, and facilities
- Manage preparation and delivery of communication pieces (newsletters, season appeals, etc.) on events, research accomplishments and other faculty/research staff/student successes
- Interpret MIT and HMS administrative and personnel policies for staff and faculty and take a leadership role in the formulation of IMES’ and HST’s policies
- Prepare regular and ad hoc reports (e.g. President’s Report, annual budget plan) and manage special projects as assigned by the Director of IMES and the Director of the HST Program at HMS
Bachelor’s degree required, Master’s degree in business, health care, administration or related field preferred. Minimum of seven years’ senior administrative experience in a university or hospital environment is required. The successful candidate will have outstanding interpersonal skills, demonstrated organizational skills, effective oral and written communication ability and discretion. Must have managerial experience and the ability to build and mentor a strong management team. Experience in the management of complex change and conflicting priorities required. Strong financial and analytical skills and experience in the education, not-for-profit, and/or research environment essential. Must be able to handle deadlines and prioritize work and to handle details while maintaining a view of the big picture. Must have strong computer skills, with proficiency in use of Microsoft Office products. Experience with COEUS, SAP and databases preferred.
Supervision is received from the Director of IMES and the Director of the HST Program at HMS.
Will directly supervise IMES administrative and support staff and provide functional supervision of staff supporting IMES faculty as needed.
Please apply to position 15310 through the MIT jobs portal at http://jobs.mit.edu. Posted October 16, 2017
Technical Associate I – IMES/Shalek Lab
Position is within the Shalek Lab (shaleklab.com, MIT, Broad Institute and Ragon Institute). The Shalek Lab specializes in leveraging novel single-cell genomic approaches to understand the behaviors of complex biological systems. The position will allow the applicant to gain experience in this field, with a specific focus in infectious disease, specifically Lyme, West Nile, and Influenza. Research questions in the lab also extend to cancer and autoimmunity, thus, the individual will gain exposure to a range of immunological research. The individual will be under the direct supervision of Prof. Alex Shalek and work within the community of graduate students and postdoctoral fellows in the lab. The applicant will learn how to implement Seq-Well, a newly developed technique in the Shalek lab, to generate single cell RNA-sequencing libraries on clinical samples. The individual will manage the receipt of clinical samples and interface with collaborators. The applicant will learn how to process and handle various tissues to be profiled with Seq-Well, including blood and synovial fluids. The applicant will also be expected to learn and perform next generation sequencing (NGS), analyze generated data in R, and communicate results to the lab and larger community. It is also expected that the applicant become proficient in the basic immunology of the infectious diseases being studied (ie: through reading papers, discussion with the lab, and attending talks/seminars). The individual will gain fundamental skills working in an interdisciplinary and technologically driven environment and gain access to the intellectual resources present across all three institutes.
Bachelor’s degree, preferably with course work in biology, chemistry, and/or genomics, and at least two years of bench experience which may include undergraduate work. Must have strong time management and communication skills to balance multiple projects, demonstrated problem solving skills, and the ability to learn quickly. Knowledge of R (and/or other programming languages) is desirable. Ability to work independently and as part of a team. This is a one year position with possibility of renewal contingent on grant funding.
Please apply to position 14987 through the MIT jobs portal at http://jobs.mit.edu. Posted July 18, 2017
Senior Faculty – IMES
SENIOR FACULTY MEMBER, The Institute for Medical Engineering and Science (IMES) http://imes.mit.edu/ at the Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts invites applicants to apply for a tenured faculty position in the area of biomedical imaging to begin July, 2017 or thereafter. The successful candidate will be appointed to a tenured faculty position at MIT as the Athinoula A. Martinos Professor. The successful candidate is expected to work closely with the Athinoula A. Martinos Center for Functional and Structural Biomedical Imaging, in particular the facilities housed at Massachusetts General Hospital (MGH). The Martinos Professor will have her/his laboratory at the Athinoula A. Martinos Center on the MGH campus. IMES is pioneering novel research and graduate education paradigms at the convergence of engineering, science, and medicine. IMES also houses the Harvard-MIT Health Science and Technology (HST) program, the Medical Electronic Device Realization Center, the Center for Microbiome Informatics and Therapeutics, and MIT’s Clinical Research Center. Appointments will be made in partnership with another MIT department. Applicants should hold a PhD in engineering, science, or a related field (including MD or MD/PhD) by the beginning of employment. The candidate should have demonstrated excellence in original research and teaching. The successful candidate will be expected to fulfill all teaching, research and service obligations of a tenured faculty professor at MIT. Faculty duties include teaching at the undergraduate and graduate levels, advising students, conducting original scholarly research, developing course materials at the graduate and undergraduate levels, and service to MIT and the profession.
Interested candidates should submit application materials electronically at http://imes-senior-search.mit.edu/register. Each application should include: curriculum vitae; the names and addresses of three or more references; a strategic statement of research interests; and a statement of teaching interests. Each candidate must arrange for reference letters to be uploaded at http://imes-senior-search.mit.edu/letters.
Questions should be addressed to firstname.lastname@example.org. To be considered responses must be received by April 1, 2017.
With MIT’s strong commitment to diversity in engineering education, research, and practice we especially encourage minorities and women to apply.
MIT is an Equal Opportunity/Affirmative Action employer.
For general questions, technical issues, or problems submitting documents, please contact Search-Master@School-of-Engineering-Faculty-Search.mit.edu.